Charles C. Wykoff, MD, PhD

Meet Dr. Wykoff

Dr. Charles C. Wykoff is a board-certified retina surgeon and ophthalmologist with Retina Consultants of Houston. Leading a top international research facility for vitreoretinal diseases, Dr. Wykoff serves as Director of Research at RCH and the Greater Houston Retina Research Foundation (GHRRF). In addition, he serves as the elected Deputy Chair of Ophthalmology for the Blanton Eye Institute, Houston Methodist Hospital. Dr. Wykoff was awarded the American Academy of Ophthalmology Achievement Award in 2015, the American Society of Retina Specialists Honor Award in 2016 and Senior Honor Award in 2018, and was appointed to the OSN Retina 150 in 2016 as an Innovator in Medical and Surgical Retina.

Skills and Specialties

Dr. Wykoff has extensive expertise in clinical trial design and coordination, as well as translational research, publishing over 100 peer-reviewed scientific articles. His research interests pertain to angiogenesis and retinal vascular diseases including age-related macular degeneration, diabetic retinopathy, and venous occlusive diseases, as well as vitreoretinal surgical topics such as retinal tears and retinal detachments, as well as macular surgery for macular holes and macular puckers. He is highly trained and skilled to perform a variety of surgical procedures, and also works with patients to hold off surgery as long as possible with conservative, nonsurgical treatment when possible.

Education and Training

He graduated Phi Beta Kappa from MIT, received his PhD from Oxford University in England while on a Marshall Scholarship, and his medical degree from Harvard Medical School. As a medical student, he co-authored the book Fighting Global Blindness. Dr. Wykoff completed his ophthalmology residency and vitreoretinal fellowship at Bascom Palmer Eye Institute, the top-rated eye hospital in the country. While there, he was awarded a Heed Fellowship, the Ronald G. Michels Fellowship Award (the nation’s highest honor for a retina surgery fellow), and served as Chief Resident/Co-Director of Ocular Trauma.


Dr. Wykoff is an elected member of the Retina Society and the Macula Society, and performs editorial responsibilities including serving as a founding member of the Ophthalmology Retina Editorial Board. Dr. Wykoff holds leadership positions in many scholarly societies including actively serving as the Academic Program Director for the Vit-Buckle Society.

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